You must understand that bipolar disorder is a kind of condition which affects all types of individuals. Children and adults are affected by this condition. This is a fact that you should know. Women would suffer the most from this kind of depression that is called bipolar depression disorder.
It is not strange in any case since even if women suffer from such regular bipolar kind of depression or a depressive disorder, they would spend more time depressed than they do being manic. This isn’t to say that only the women are depressive, the men also are and they may get affected by such condition.
The bipolar type of disorder is known as manic depression because this is a mental condition wherein you would interchange often between the phases of mania and depression. If you suffer from such bipolar depression, you won’t have to spend a lot of time being manic as you spend getting depressed.
This kind of depression is one form of disorder and you should understand it is easy to wrongly diagnose as bipolar disorder due to the similarity of such symptoms. Because of this, the doctor must have to keep you around for a long time when they would try to diagnose the condition that you have. It is surely not flattering to either of you when you get treated for a wrong thing.
The bipolar affective disorder is another name for such bipolar disorder or the manic-depressive illness. But, you don’t like to mistake this for bipolar depression disorder. This is closely related with the symptoms of the depressive phase of the bipolar disorder but just a few of the mania.
Monotherapy trials against the placebo is the gold-standard design when determining the efficacy in treating bipolar depression. When such efficacy would be proven as monotherapy, the new compounds can be tested in the adjunctive-medication placebo-controlled trials. Those younger adults, without such established need for the long-term medication can be suitable for those clinical trials that require placebo-controls. The switch to mania or such hypomania can be a consequence of the active treatment for such bipolar depression.
Some medications like the tricyclic antidepressants as well as venlafaxine can be more likely to prove switch unlike the others but such increased rate of the switch can’t be seen until around ten weeks of treatment. Thus, the 12-week trials against placebo are needed to determine the risk of switch and establish the continuing effects. You should know that careful assessment at 6-8 weeks are required to make sure that the patients who fail to respond won’t continue in the study for the unacceptable periods of time.